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Kupitz C, Olmos Jr. J, Holl M, Tremblay L, Pande K, Pandey S, Oberthür D, Hunter M, Liang M, Aquila A, Tenboer J, Calvey G, Katz A, Chen Y, Wiedorn M, Knoska J, Meents A, Majriani V, Norwood T, Poudyal I, Grant T, Miller M, Xu W, Tolstikova A, Morgan A, Metz M, Martin-Garcia J, Zook J, Roy-Chowdhury S, Coe J, Nagaratnam N, Meza D, Fromme R, Basu S, Frank M, White T, Barty A, Bajt S, Yefanov O, Chapman H, Zatsepin N, Nelson G, Weierstall U, Spence J, Schwander P, Pollack L, Fromme P, Ourmazd A, PhillipsJr. G, Schmidt M. Structural enzymology using X-ray free electron lasers. Struc Dyn. 2017 Dec; 4(4):044003

Fuller F, Gul S, Chatterjee R, Burgie E, Young I, Lebrette H, Srinivas V, Brewster A, Michels-Clark T, Clinger J, Andi B, Ibrahim M, Pastor E, de Lichtenberg C, Hussein R, Pollock C, Zhang M, Stan C, Kroll T, Fransson T, Weninger C, Kubin M, Aller P, Lassalle L, Brauer P, Miller M, Amin M, Koroidov S, Roessler C, Allaire M, Sierra R, Docker P, Glownia J, Nelson S, Koglin J, Zhu D, Chollet M, Song S, Lemke H, Liang M, Sokaras D, Alonso-Mori R, Zouni A, Messinger J, Bergmann U, Boal A, Bollinger Jr J, Krebs C, Hogbom M, Phillips Jr G, Vierstra R, Sauter N, Orville A,  Kern J, Yachandra V, Yano J. Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers. Nat Methods. 2017 Apr;14(4):443-449.


Cao H, Tan K, Wang F, Bigelow L, Yennamalli RM, Jedrzejczak R, Babnigg G, Bingman CA, Joachimiak A, Kharel MK, Singh S, Thorson JS, Phillips GN Jr. Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Struct Dyn. 2016 May;3(3):34702.

Rudolf JD, Bigelow L, Chang C, Cuff ME, Lohman JR, Chang CY, Ma M, Yang D, Clancy S, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry. 2015 Nov 17;54(45):6842-5.
PMID: 26512730
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Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, Yennamalli RM, Bingman CA, Joachimiak A, Thorson JS, Phillips GN Jr. Structural Characterization of CalS8, a TDP-α-d-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis. J Biol Chem. 2015 Oct 23;290(43):26249-58.
Lohman JR, Ma M, Osipiuk J, Nocek B, Kim Y, Chang C, Cuff M, Mack J, Bigelow L, Li H, Endres M, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12693-8.
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Samuel PP, Smith LP, Phillips GN Jr, Olson JS. Apoglobin Stability Is the Major Factor Governing both Cell-free and in Vivo Expression of Holomyoglobin. J Biol Chem. 2015 Sep 25;290(39):23479-95
PMID: 26205820
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Wang F, Singh S, Xu W, Helmich KE, Miller MD, Cao H, Bingman CA, Thorson JS, Phillips GN Jr. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. ACS Chem Biol. 2015 Sep 18;10(9):2048-56.
PMID: 26023720
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Singh S, Kim Y, Wang F, Bigelow L, Endres M, Kharel MK, Babnigg G, Bingman CA, Joachimiak A, Thorson JS, Phillips GN Jr. Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis. Proteins. 2015 Aug;83(8):1547-54.
PMID: 26061967
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Aceti DJ, Bingman CA, Wrobel RL, Frederick RO, Makino S, Nichols KW, Sahu SC, Bergeman LF, Blommel PG, Cornilescu CC, Gromek KA, Seder KD, Hwang S, Primm JG, Sabat G, Vojtik FC, Volkman BF, Zolnai Z, Phillips GN Jr, Markley JL, Fox BG. Expression platforms for producing eukaryotic proteins: a comparison of E. coli cell-based and wheat germ cell-free synthesis, affinity and solubility tags, and cloning strategies. J Struct Funct Genomics. 2015 Jun;16(2):67-80.
PMID: 25854603
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Kim DJ, Bitto E, Bingman CA, Kim HJ, Han BW, Phillips GN Jr. Crystal structure of the protein At3g01520, a eukaryotic universal stress protein-like protein from arabidopsis thaliana in complex with AMP. Proteins. 2015 Apr 28.
PMID: 25921306
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Traeger LL, Volkening JD, Moffett H, Gallant JR, Chen PH, Novina CD, Phillips GN Jr, Anand R, Wells GB, Pinch M, Güth R, Unguez GA, Albert JS, Zakon H, Sussman MR, Samanta MP. Unique patterns of transcript and miRNA expression in the South American strong voltage electric eel (Electrophorus electricus). BMC Genomics. 2015 Mar 26;16:243.
PMID: 25887781
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Weerth RS, Michalska K, Bingman CA, Yennamalli RM, Li H, Jedrzejczak R, Wang F, Babnigg G, Joachimiak A, Thomas MG, Phillips GN Jr. Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution. Proteins. 2015 Feb;83(2):383-8.
PMID: 25354690
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Auldridge ME, Cao H, Sen S, Franz LP, Bingman CA, Yennamalli RM, Phillips GN Jr, Mead D, Steinmetz EJ. LucY: A Versatile New Fluorescent Reporter Protein. PLoS One. 2015 Apr 23;10(4):e0124272.
PMID: 25906065
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Karkehabadi S, Helmich KE, Kaper T, Hansson H, Mikkelsen NE, Gudmundsson M, Piens K, Fujdala M, Banerjee G, Scott-Craig JS, Walton JD, Phillips GN Jr, Sandgren M. Biochemical characterization and crystal structures of a fungal family 3 β-glucosidase, Cel3A from Hypocrea jecorina. J Biol Chem. 2014 Nov 7;289(45):31624-37.
PMID: 25164811
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Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, Kennedy MA, Bingman CA, Zhu H, Phillips GN Jr, Thorson JS. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. ACS Chem Biol. 2014 Oct 17;9(10):2347-58.
PMID: 25079510
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Moon S, Bannen RM, Rutkoski TJ, Phillips GN Jr, Bae E. Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases. Proteins. 2014 Oct;82(10):2631-42.
PMID: 24931334
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Desai KK, Bingman CA, Cheng CL, Phillips GN Jr, Raines RT. Structure of RNA 3'-phosphate cyclase bound to substrate RNA. RNA. 2014 Oct;20(10):1560-6. doi: 10.1261/rna.045823.114. Epub 2014 Aug 26.
PMID: 25161314
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Cao H, Walton JD, Brumm P, Phillips GN Jr. Structure and substrate specificity of a eukaryotic fucosidase from Fusarium graminearum. J Biol Chem. 2014 Sep 12;289(37):25624-38.
PMID: 25086049
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Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN Jr. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. FEBS J. 2014 Sep;281(18):4224-39.
PMID: 24649856
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Moon S, Jung DK, Phillips GN Jr, Bae E. An integrated approach for thermal stabilization of a mesophilic adenylate kinase. Proteins. 2014 Sep;82(9):1947-59.
PMID: 24615904
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Lomax JE, Bianchetti CM, Chang A, Phillips GN Jr, Fox BG, Raines RT. Functional evolution of ribonuclease inhibitor: insights from birds and reptiles. J Mol Biol. 2014 Aug 26;426(17):3041-56.
PMID: 24941155
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Lohman JR, Ma M, Cuff ME, Bigelow L, Bearden J, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins. Proteins. 2014 Jul;82(7):1210-8.
PMID: 25050442
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Gallant JR, Traeger LL, Volkening JD, Moffett H, Chen PH, Novina CD, Phillips GN Jr, Anand R, Wells GB, Pinch M, Güth R, Unguez GA, Albert JS, Zakon HH, Samanta MP, Sussman MR. Nonhuman genetics. Genomic basis for the convergent evolution of electric organs.Science. 2014 Jun 27;344(6191):1522-5.
PMID: 24970089
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Yennamalli R, Arangarasan R, Bryden A, Gleicher M, Phillips GN Jr. Using a commodity high-definition television for collaborative structural biology. J Appl Crystallogr. 2014 May 29;47(Pt 3):1153-1157.
PMID: 24904249
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Desai KK, Cheng CL, Bingman CA, Phillips GN Jr, Raines RT. A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation. Nucleic Acids Res. 2014 Apr;42(6):3931-42.
PMID: 24435797
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Book AJ, Yennamalli RM, Takasuka TE, Currie CR, Phillips GN Jr, Fox BG. Evolution of substrate specificity in bacterial AA10 lytic polysaccharide monooxygenases. Biotechnol Biofuels. 2014 Aug 6;7:109.
PMID: 25161697
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Park MS, Bitto E, Kim KR, Bingman CA, Miller MD, Kim HJ, Han BW, Phillips GN Jr. Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway. PLoS One. 2014 Oct 30;9(10):e111142.
PMID: 25356641
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Bianchetti CM, Brumm P, Smith RW, Dyer K, Hura GL, Rutkoski TJ, Phillips GN Jr. Structure, dynamics, and specificity of endoglucanase D from Clostridium cellulovorans. J Mol Biol. 2013 Nov 15;425(22):4267-85.
PMID: 23751954
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Smith DW, Han MR, Park JS, Kim KR, Yeom T, Lee JY, Kim do J, Bingman CA, Kim HJ, Jo K, Han BW, Phillips GN Jr. Crystal structure of the protein from Arabidopsis thaliana gene At5g06450, a putative DnaQ-like exonuclease domain-containing protein with homohexameric assembly. Proteins. 2013 Sep;81(9):1669-75.
PMID: 23616405
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Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN Jr, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol. 2013 Jul 19;8(7):1632-9.
PMID: 23662776
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Wang F, Zhou M, Singh S, Yennamalli RM, Bingman CA, Thorson JS, Phillips GN Jr. Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins. 2013 Jul;81(7):1277-82.
PMID: 23526584
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Desai KK, Bingman CA, Phillips GN Jr, Raines RT. Structures of the noncanonical RNA ligase RtcB reveal the mechanism of histidine guanylylation. Biochemistry. 2013 Apr 16;52(15):2518-25.
PMID: 23560983
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Lohman JR, Bingman CA, Phillips GN Jr, Shen B. Structure of the bifunctional acyltransferase/decarboxylase LnmK from the leinamycin biosynthetic pathway revealing novel activity for a double-hot-dog fold. Biochemistry. 2013 Feb 5;52(5):902-11.
PMID: 23320975
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Burgie ES, Walker JM, Phillips GN Jr, Vierstra RD. A photo-labile thioether linkage to phycoviolobilin provides the foundation for the blue/green photocycles in DXCF-cyanobacteriochromes. Structure. 2013 Jan 8;21(1):88-97.
PMID: 23219880
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Daily MD, Yu H, Phillips GN Jr, Cui Q. Allosteric activation transitions in enzymes and biomolecular motors: insights from atomistic and coarse-grained simulations. Top Curr Chem. 2013;337:139-64.
PMID: 23468286
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